@article{16572,
  author = {Arima Hisatomi and Wang J. and Heritier Stephane and Wong L. and Li Z. and Heeley Emma and Wei J. and Huang Y. and Anderson Craig},
  title = {Comparison of recovery patterns and prognostic indicators for ischemic and hemorrhagic stroke in China: the ChinaQUEST (QUality Evaluation of Stroke Care and Treatment) Registry study},
  abstract = {<p>
BACKGROUND AND PURPOSE: Limited data exist on the comparative recovery patterns and outcomes of patients with ischemic stroke and intracerebral hemorrhage in China. METHODS: Data on baseline characteristics and outcomes of 6354 patients at 3 and 12 months poststroke are from ChinaQUEST (QUality Evaluation of Stroke Care and Treatment), a multicenter, prospective, 62-hospital registry study in China. Logistic regression was used to determine factors associated with a poor outcome defined by death/dependency (modified Rankin Scale score of 3 to 5) on follow-up. Generalized estimating equations were used to assess variations in recovery pattern by stroke type. RESULTS: Baseline severity and rate of functional recovery in the early phase were significantly greater for intracerebral hemorrhage. However, patients with ischemic stroke were on average twice as likely to experience a good outcome (modified Rankin Scale score &lt;3) by 12 months poststroke (OR: 1.98, CI: 1.76 to 2.24). In patients with ischemic stroke, diabetes and atrial fibrillation were strongly associated with a poor outcome at 12 months poststroke even after adjustment for confounding factors such as age, prior stroke/dependency, time to presentation, and stroke severity, whereas use of antiplatelets and lipid-lowering therapy after stroke were associated with improved outcome. For patients with intracerebral hemorrhage, low education and atrial fibrillation were associated with a poor outcome after adjustment for potential confounders and antihypertensive use was strongly associated with improved outcome. CONCLUSIONS: Patients with intracerebral hemorrhage and ischemic stroke have different recovery patterns in China. However, they share similar prognostic factors and in the use of evidence-based secondary prevention therapies to maximize chances of a good outcome.
</p>
},
  year = {2010},
  journal = {Stroke},
  volume = {41},
  edition = {2010/07/24},
  number = {9},
  pages = {1877-83},
  isbn = {1524-4628 (Electronic)0039-2499 (Linking)},
  note = {Wei, Jade WHeeley, Emma LWang, Ji-GuangHuang, YiningWong, Lawrence K SLi, ZhengyiHeritier, StephaneArima, HisatomiAnderson, Craig SChinaQUEST InvestigatorsMulticenter StudyResearch Support, Non-U.S. Gov'tUnited StatesStroke; a journal of cerebral circulationStroke. 2010 Sep;41(9):1877-83. Epub 2010 Jul 22.},
  language = {eng},
}