@article{17193, author = {Chervin R. and Kushida C. and Lewin D. and Malow B. and Redline S. and Goldman E. and Brown D. and Anderson Craig}, title = {Ethical issues in the conduct of clinical trials in obstructive sleep apnea}, abstract = {
Scientifically rigorous clinical trials are needed to test continuous positive airway pressure's (CPAP) effect on important clinical endpoints known to be associated with obstructive sleep apnea, such as myocardial infarction, cardiac arrhythmias, stroke, mortality, seizures, and cognitive function. In this "Special Article," we review the regulatory and ethical issues that surround the design and conduct of CPAP trials, including selection of the appropriate control condition, exclusion criteria, and follow-up duration.
}, year = {2011}, journal = {Journal of Clinical Sleep Medicine}, volume = {7}, edition = {2011/02/24}, number = {1}, pages = {103-8}, isbn = {1550-9397 (Electronic)1550-9389 (Linking)}, note = {Brown, Devin LAnderson, Craig SChervin, Ronald DKushida, Clete ALewin, Daniel SMalow, Beth ARedline, SusanGoldman, Edward BUnited StatesJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep MedicineJ Clin Sleep Med. 2011 Feb 15;7(1):103-8.}, language = {eng}, }