@article{21923,
  author = {Rodgers A and Perkovic Vlado},
  title = {Redefining Blood-Pressure Targets - SPRINT Starts the Marathon},
  abstract = {<p>
Blood pressure is a potent determinant of cardiovascular risk, but the most appropriate targets for blood-pressure lowering have long been debated. Observational studies with a low risk of confounding have shown a linear relationship between blood pressure and cardiovascular risk down to 115/75 mm Hg,1 but some observational studies with a greater potential for confounding, involving persons at increased risk, have suggested a J-shaped curve - that is, below a given blood pressure, risk would increase. When trials of blood-pressure-lowering drugs have shown benefits in patients without hypertension, these effects have often been ascribed to alternative mechanisms. The widespread uncertainty . . .
</p>
},
  year = {2015},
  journal = {New England Journal of Medicine.},
  volume = {373},
  edition = {2015/11/10},
  number = {22},
  pages = {2175-8},
  isbn = {1533-4406 (Electronic)<br/>0028-4793 (Linking)},
  note = {Perkovic, Vlado<br/>Rodgers, Anthony<br/>N Engl J Med. 2015 Nov 9.},
  language = {Eng},
}