01662nas a2200181   4500000000100000008004100001100001500042700002200057700001800079700001500097700001500112245007800127250001500205300000900220490001500229520119000244020004601434       2010                            d1 aGrobbee D.1 avan der Schouw Y.1 avan Dieren S.1 aBeulens J.1 aNeal Bruce00aThe global burden of diabetes and its complications: an emerging pandemic  a2010/05/28  aS3-80 v17 Suppl 13 a<p>
The number of patients with type 2 diabetes is increasing rapidly in both developed and developing countries around the world. The emerging pandemic is driven by the combined effects of population ageing, rising levels of obesity and inactivity, and greater longevity among patients with diabetes that is attributable to improved management. The vascular complications of type 2 diabetes account for the majority of the social and economic burden among patients and society more broadly. This review summarizes the burden of type 2 diabetes, impaired glucose tolerance, and their vascular complications. It is projected that by 2025 there will be 380 million people with type 2 diabetes and 418 million people with impaired glucose tolerance. Diabetes is a major global cause of premature mortality that is widely underestimated, because only a minority of persons with diabetes dies from a cause uniquely related to the condition. Approximately one half of patients with type 2 diabetes die prematurely of a cardiovascular cause and approximately 10% die of renal failure. Global excess mortality attributable to diabetes in adults was estimated to be 3.8 million deaths.
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