01563nas a2200205   4500000000100000008004100001100002000042700001900062700001200081700001700093700001400110700001400124700001500138245009700153250001500250300000900265490000800274520102400282020005101306       2015                            d1 aRosenbaum Simon1 aVancampfort D.1 aWard P.1 aGuelinkcx H.1 aProbst M.1 aStubbs B.1 aDe Hert M.00aAssociations between metabolic and aerobic fitness parameters in patients with schizophrenia  a2014/12/11  a23-70 v2033 a<p>
The primary aim was to determine whether the presence of metabolic syndrome (MetS) limits aerobic fitness in patients with schizophrenia. A secondary aim was to investigate the associations between aerobic fitness and MetS parameters. Aerobic fitness (expressed as predicted maximal oxygen uptake) was assessed using the Astrand-Rhyming test. Those with MetS (n = 19) were similar in age, sex, antipsychotic medication use, symptoms, and smoking behavior than those without (n = 31). Estimated maximal oxygen uptake was 21.4% lower (p = 0.001) in patients with MetS than in patients without MetS (29.5 +/- 7.4 ml of O2/min/kg vs. 37.5 +/- 8.2 ml of O2/min/kg, respectively). The estimated maximal oxygen uptake of the entire sample was correlated with waist circumference, the level of high-density lipoproteins, and fasting glucose. The current study demonstrates that the additive burden of MetS might place people with schizophrenia at increased risk for functional limitations in daily life activities.
</p>
  a1539-736X (Electronic)<br/>0022-3018 (Linking)