01605nas a2200253   4500000000100000008004100001260001700042100001300059700001300072700001200085700001100097700001200108700001400120700001200134700001200146700001400158700002000172700001300192700001700205245007100222250001500293520099200308020005101300       2016                            d  c1694568527831 aYadav A.1 aKumar V.1 aModi G.1 aJha V.1 aJohn O.1 aPrasad N.1 aGang S.1 aOjha J.1 aPandey R.1 aParameswaran S.1 aSahay M.1 aVarughese S.00aThe Indian Chronic Kidney Disease (ICKD) Study: Design and Methods  a2016/04/123 a<p>
BACKGROUND: The rate and factors that influence progression of chronic kidney disease (CKD) in developing countries like India are unknown. A pan-country prospective, observational cohort study is needed to address these knowledge gaps. METHODS: The Indian Chronic Kidney Disease (ICKD) study will be a cohort study of approximately 5000 patients with mild to moderate CKD presenting to centers that represent different geographical regions in India. Time to 50% decline in baseline estimated glomerular filtration rate, need of renal replacement therapy or any new cardiovascular disease (CVD) event or death from CVD are the primary end points. VALUE OF STUDY: This study will provide the opportunity to determine risk factors for CKD progression and development of CVD in Indian subjects and perform international comparisons to determine ethnic and geographical differences. A bio-repository will provide a chance to discover biomarkers and explore genetic risk factors.
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  a1440-1797 (Electronic)<br/>1320-5358 (Linking)