Muscle power, muscle strength and postural sway are considered to be determinants of fall risk and gait in Parkinson's disease (PD) and potential targets for therapeutic trials. However, the potential usefulness of these tests as outcome measures depends on their reproducibility in the PD population. Therefore, measures of leg muscle power, leg muscle strength, postural sway and mobility were taken on two occasions 1week apart in 31 people with PD. Measures of muscle power, muscle strength and mobility were found to be very reliable (intraclass correlation coefficients (ICC(3,1) 0.50-0.97)) and showed good agreement, i.e. small measurement error. Postural sway measures showed poor reliability (ICC(3,1) 0.04-0.51) and agreement, especially in the presence of disabling dyskinesia. The moderate to high reproducibility of leg muscle power, muscle strength and mobility measures in people with PD confirm their suitability as outcomes measures in clinical and research settings. Further research into the clinical measurement of postural sway in people with PD is warranted, especially in individuals with dyskinesia.
AD - Clinical & Rehabilitation Sciences Research Group, Faculty of Health Sciences, The University of Sydney, Sydney, Australia. AN - 22640867 BT - Gait and Posture DP - NLM ET - 2012/05/30 LA - Eng N1 - Paul, Serene SCanning, Colleen GSherrington, CatherineFung, Victor S CGait Posture. 2012 May 26. N2 -Muscle power, muscle strength and postural sway are considered to be determinants of fall risk and gait in Parkinson's disease (PD) and potential targets for therapeutic trials. However, the potential usefulness of these tests as outcome measures depends on their reproducibility in the PD population. Therefore, measures of leg muscle power, leg muscle strength, postural sway and mobility were taken on two occasions 1week apart in 31 people with PD. Measures of muscle power, muscle strength and mobility were found to be very reliable (intraclass correlation coefficients (ICC(3,1) 0.50-0.97)) and showed good agreement, i.e. small measurement error. Postural sway measures showed poor reliability (ICC(3,1) 0.04-0.51) and agreement, especially in the presence of disabling dyskinesia. The moderate to high reproducibility of leg muscle power, muscle strength and mobility measures in people with PD confirm their suitability as outcomes measures in clinical and research settings. Further research into the clinical measurement of postural sway in people with PD is warranted, especially in individuals with dyskinesia.
PY - 2012 SN - 1879-2219 (Electronic)0966-6362 (Linking) ST - G T2 - Gait and Posture TI - Reproducibility of measures of leg muscle power, leg muscle strength, postural sway and mobility in people with Parkinson's disease ER -