TY - JOUR
KW - Adult
KW - Female
KW - Humans
KW - Aged
KW - Male
KW - Middle Aged
KW - Risk Factors
KW - Prognosis
KW - Adolescent
KW - Severity of Illness Index
KW - Research Design
KW - Prospective Studies
KW - Time Factors
KW - Cardiovascular Diseases
KW - Young Adult
KW - India
KW - Kidney Failure, Chronic
KW - Renal Replacement Therapy
KW - biomarkers
KW - Disease Progression
KW - Glomerular Filtration Rate
KW - Genetic Predisposition to Disease
KW - Biological Specimen Banks
KW - Kidney
KW - Renal Insufficiency, Chronic
AU - Jha V.
AU - John O.
AU - Kumar Vivek
AU - Yadav Ashok
AU - Gang Sishir
AU - Modi Gopesh
AU - Ojha Jai
AU - Pandey Rajendra
AU - Parameswaran Sreejith
AU - Prasad Narayan
AU - Sahay Manisha
AU - Varughese Santosh
AU - Baid-Agarwal Seema
AB - <p>
<b>AIM: </b>The rate and factors that influence progression of chronic kidney disease (CKD) in developing countries like India are unknown. A pan-country prospective, observational cohort study is needed to address these knowledge gaps.
</p>

<p>
<b>METHODS: </b>The Indian Chronic Kidney Disease (ICKD) study will be a cohort study of approximately 5000 patients with mild to moderate CKD presenting to centres that represent different geographical regions in India. Time to 50% decline in baseline estimated glomerular filtration rate, need of renal replacement therapy or any new cardiovascular disease (CVD) event or death from CVD are the primary end points.
</p>

<p>
<b>VALUE OF STUDY: </b>This study will provide the opportunity to determine risk factors for CKD progression and development of CVD in Indian subjects and perform international comparisons to determine ethnic and geographical differences. A bio-repository will provide a chance to discover biomarkers and explore genetic risk factors.
</p>

BT - Nephrology (Carlton)
C1 - https://www.ncbi.nlm.nih.gov/pubmed/27062078?dopt=Abstract
DO - 10.1111/nep.12789
IS - 4
J2 - Nephrology (Carlton)
LA - eng
N2 - <p>
<b>AIM: </b>The rate and factors that influence progression of chronic kidney disease (CKD) in developing countries like India are unknown. A pan-country prospective, observational cohort study is needed to address these knowledge gaps.
</p>

<p>
<b>METHODS: </b>The Indian Chronic Kidney Disease (ICKD) study will be a cohort study of approximately 5000 patients with mild to moderate CKD presenting to centres that represent different geographical regions in India. Time to 50% decline in baseline estimated glomerular filtration rate, need of renal replacement therapy or any new cardiovascular disease (CVD) event or death from CVD are the primary end points.
</p>

<p>
<b>VALUE OF STUDY: </b>This study will provide the opportunity to determine risk factors for CKD progression and development of CVD in Indian subjects and perform international comparisons to determine ethnic and geographical differences. A bio-repository will provide a chance to discover biomarkers and explore genetic risk factors.
</p>

PY - 2017
SP - 273
EP - 278
T2 - Nephrology (Carlton)
TI - Indian chronic kidney disease study: Design and methods.
VL - 22
SN - 1440-1797
ER -