OBJECTIVE: Measurement of mean population Na and K intakes typically uses laboratory-based assays, which can add significant logistical burden and costs. A valid field-based measurement method would be a significant advance. In the current study, we used 24 h urine samples to compare estimates of Na, K and Na:K ratio based upon assays done using the field-based Horiba twin meter v. laboratory-based methods.
DESIGN: The performance of the Horiba twin meter was determined by comparing field-based estimates of mean Na and K against those obtained using laboratory-based methods. The reported 95 % limits of agreement of Bland-Altman plots were calculated based on a regression approach for non-uniform differences.
SETTING: The 24 h urine samples were collected as part of an ongoing study being done in rural China.
SUBJECTS: One hundred and sixty-six complete 24 h urine samples were qualified for estimating 24 h urinary Na and K excretion.
RESULTS: Mean Na and K excretion were estimated as 170·4 and 37·4 mmol/d, respectively, using the meter-based assays; and 193·4 and 43·8 mmol/d, respectively, using the laboratory-based assays. There was excellent relative reliability (intraclass correlation coefficient) for both Na (0·986) and K (0·986). Bland-Altman plots showed moderate-to-good agreement between the two methods.
CONCLUSIONS: Na and K intake estimations were moderately underestimated using assays based upon the Horiba twin meter. Compared with standard laboratory-based methods, the portable device was more practical and convenient.
BT - Public Health Nutr C1 - https://www.ncbi.nlm.nih.gov/pubmed/29306343?dopt=Abstract DA - -24271209722 DO - 10.1017/S1368980017003731 IS - 6 J2 - Public Health Nutr LA - eng N2 -OBJECTIVE: Measurement of mean population Na and K intakes typically uses laboratory-based assays, which can add significant logistical burden and costs. A valid field-based measurement method would be a significant advance. In the current study, we used 24 h urine samples to compare estimates of Na, K and Na:K ratio based upon assays done using the field-based Horiba twin meter v. laboratory-based methods.
DESIGN: The performance of the Horiba twin meter was determined by comparing field-based estimates of mean Na and K against those obtained using laboratory-based methods. The reported 95 % limits of agreement of Bland-Altman plots were calculated based on a regression approach for non-uniform differences.
SETTING: The 24 h urine samples were collected as part of an ongoing study being done in rural China.
SUBJECTS: One hundred and sixty-six complete 24 h urine samples were qualified for estimating 24 h urinary Na and K excretion.
RESULTS: Mean Na and K excretion were estimated as 170·4 and 37·4 mmol/d, respectively, using the meter-based assays; and 193·4 and 43·8 mmol/d, respectively, using the laboratory-based assays. There was excellent relative reliability (intraclass correlation coefficient) for both Na (0·986) and K (0·986). Bland-Altman plots showed moderate-to-good agreement between the two methods.
CONCLUSIONS: Na and K intake estimations were moderately underestimated using assays based upon the Horiba twin meter. Compared with standard laboratory-based methods, the portable device was more practical and convenient.
PY - 2018 SP - 1036 EP - 1042 T2 - Public Health Nutr TI - Sodium and potassium content of 24 h urinary collections: a comparison between field- and laboratory-based analysers. VL - 21 SN - 1475-2727 ER -