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Congratulations to Xia Wang, Sonali Gnanenthiran and Julieann Coombes from The George Institute for making it to onto the list of 36 female researchers awarded Federal funding to advance women in…

The current practice of intensively lowering blood glucose in critically ill patients increases the risk of death by 10%. Results of the largest trial of intensive glucose lowering in critically ill…

Recently, the George Institute for Global Health, together with Ningxia Medical University, Tufts University's Friedman School of Nutritional Sciences and Policy, and the Peking University Clinical…

Acute kidney injury (AKI) occurs in up to 20% of patients treated in intensive care units (ICU). When severe, it requires renal replacement therapy (RRT) and is associated with high healthcare costs…

Background SGLT2 inhibitors are a relatively new class of agents, originally developed as oral antihyperglycemic drugs. SGLT2 inhibitors are clinically available since 2012 for the treatment of…

A small but clinically important trial of a new ultra-low dose four-in-one pill to treat high blood pressure has produced remarkable results. Every patient on the pilot trial conducted by The George…

A global study of over 28,000 people has provided the strongest evidence to date that lowering blood pressure in later life can cut the risk of dementia. Dr Ruth Peters, Associate Professor at UNSW…

Lead author Dr Brendon Neuen from The George Institute for Global Health commented:  “We found SGLT2 inhibitors clearly and powerfully reduce the risk of kidney failure.” “These findings…

A new trial could transform the treatment of chronic kidney disease (CKD) and could benefit thousands of people in Australia. Researchers from The George Institute for Global Health have been…

The SPACE group includes collaborators conducting or planning a series of clinical trials of a polypill strategy for cardiovascular disease prevention. The polypill being evaluated in these trials is…

With more than 5,000 patients participating, the "INTERACT3" study is now the world's largest clinical trial of acute intracerebral haemorrhage (ICH), according to the research team in China.  …

Current status– recruiting    TRIDENT is an international medical research study which aims to determine the effect of more intensive blood pressure control to prevent recurrent stroke in…

Background Acute Kidney Injury (AKI) affects up to 1 in 2 patients treated in the ICU, and is associated with poorer survival, reductions in long term kidney function and greater cost of treatment.…

Hyperglycaemia (high blood sugar) is a common finding in patients in the intensive care unit (ICU), whether or not the patient has a history of diabetes mellitus. Internationally, intensive blood…

The world’s first international polypill trial has shown that a four in one combination pill can halve predicted heart disease and stroke risk. Results were published today in the open access…

Background An abdominal aortic aneurysm (AAA) is an enlarged area in the lower part of the major vessel that supplies blood to the body. Most AAAs are detected when they are small, and affected…

The George Institute for Global Health has partnered with Cardio Union, a leading private Chinese healthcare organization focused on the prevention and treatment of cardiology conditions, to create…

New research from The George Institute for Global Health and the University of Sydney has found that opioid painkillers, a common treatment for low back pain, provide minimal benefit. The findings…

People undergoing X-rays often require an intravenous contrast injection to improve the quality of the information obtained. Some of these patients will develop acute kidney injury as a result, and…

Background: Angiotensin Receptor Blockers (ARBs) inhibit the Angiotensin II Type 1 Receptor (AT1R). In the non-COVID-19 setting, AT1R promotes vasoconstriction, inflammation and fibrosis, and…