Pre-Budget Submission 2021–22 - Building Back Better: Investing in Five Medical Research Ideas
Policy & Practice Report
Centre of Research Excellence: Healthy Food, Healthy Planet, Healthy People
Millions of Australians and hundreds of millions of people around the world suffer from conditions caused by excessive consumption of unhealthy foods and insufficient intake of healthy foods. The food system is one of the largest contributors to environmental degradation through greenhouse gas emissions, water use and deforestation, and one of the sectors hardest hit by climate change. Access to information about the nutritional quality and environmental impacts of the food we eat is a basic consumer right, yet is lacking.
The Healthy Food, Healthy Planet, Healthy People Centre for Research Excellence will deliver world-leading innovations in nutrient profiling algorithms and environmental indicators that estimate the human and planetary consequences of varying patterns of food and beverage consumption.
The project will: Identify effective means of conveying combined nutrition and sustainability information. Use the developed algorithms, environmental indicators and user response data
INTErGenerational intervention to Reduce fraIlTY trial (INTEGRITY)
BackgroundIt is a huge achievement that we are living longer than before but sometimes older age also comes with poorer health. Frailty, defined as having an increased vulnerability, and dementia or cognitive decline are more common at older ages and often result in heightened care requirements and transition to aged care. Approximately 12-24 percent of older adults are identified as frail, while an additional 40 percent are categorized as 'prefrail' or mildly frail, and around 10% of adults over 65 have a diagnosis of dementia.But what if we could reduce the risk of becoming frail and help to protect our brain health and thinking or cognitive skills? We know that having greater physical activity, social engagement and using our brains in cognitive activities are linked to lowering the risk of developing frailty and cognitive decline. Increasing these aspects of our day to day life may help us. A fun way to do this can be through intergenerational practice.Intergenerational practice unites different generatio
ACT-GLOBAL: A multi-faCtorial, mulTi-arm, multi-staGe, randomised, gLOBal Adaptive pLatform trial for stroke
Background
Stroke remains a leading cause of death and disability worldwide. Despite advances in medical technology and treatment strategies, many patients still do not achieve optimal outcomes. The George Institute’s ACT-GLOBAL study is an adaptive platform trial that is aiming to address the urgent need for the development of new and more effective interventions for stroke patients across the world.
A platform trial involves study of several different clinical questions at the same time, essentially uniting multiple clinical trials or ‘Domains’ under a single organisational structure lead by experts in the field. Adaptive design allows the team to add or collapse (if needed) research questions during the trial as more information is collected. We believe the adaptive platform approach is a uniquely flexible and efficient way to conduct ground-breaking research.
The ACT-GLOBAL platform currently has several domains across the stroke-subtypes of Acute Ischemic Stroke, where a bloc
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