Clinical and community trials
Our approach is consistent with the WHO Global Clinical Trial Forum’s vision of supporting the development of “sustained national and global clinical trial capacity during and between crises ensures clinical research and trials are integrated and sustained in all health systems so that trials can help improve health outcomes for all, all the time”.
Designing high quality trials
Our clinical and community trials span a wide range of therapeutic areas, along with innovative approaches in design and conduct.
Our focus includes the following:
Enhancing diversity in clinical trials
Clinical trials often underrepresent women, First Nations people, and diverse communities. The George Institute works to address barriers, report on diversity, and implement co-designed strategies to reflect real populations. Communities are involved throughout the process, ensuring trials are relevant and impactful.
Integrating planetary health in clinical trials
Climate change affects health, and trials can help address its impacts on air, water, and temperature. The George Institute also reduces its own carbon footprint, ensuring research is environmentally responsible. We strive to answer critical health questions with minimal environmental impact.
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Innovation decentralised trials
Decentralised trials let participants join from home, improving convenience and diversity. This approach expands recruitment and uses digital tools and AI for real-time data collection and patient safety. It enables trials in under-resourced settings and enhances participant engagement.
Learn moreOur clinical and community trials
Participating in clinical and community trials can improve the lives of people. Find out what trials we are currently recruiting for.
Our approach to clinical and community trials?
Clinical and community trials are research studies involving human participants to evaluate treatments like medications, vaccines, procedures, and behaviour-change interventions. They play a critical role in finding safe, effective ways to improve health, prevent diseases, and treat illnesses. Trials follow a rigorous process, from pre-clinical testing and trial phases to regulatory approval and post-marketing studies, ensuring treatments are safe and effective.
Participation in a trial allows individuals to access innovative treatments, contribute to medical advancements, and help shape future healthcare. Participants are informed of trial details, risks, and rights, including the ability to withdraw at any time. Clinical and community trials are designed to provide high-quality care, ensure safety, and inform medical guidelines through robust data collection and analysis.
Find out more about what a clinical and community trial is.
The George Institute develops impactful clinical trials by focusing on efficiency, relevance, and sustainability. We reduce research "waste" by using innovative methods like adaptive and pragmatic designs to answer critical health questions faster and more effectively. Trials are conducted with transparency, participant involvement, and environmental responsibility, recognising the need to minimise their carbon footprint.
Our work ensures trials are inclusive, addressing global health priorities and promoting diversity across participants. By collaborating with initiatives like Trial Forge and integrating real-world insights, we aim to improve trial processes and outcomes. Future trials will continue to prioritise meaningful engagement, clear communication, and methods that are relevant to underserved communities.
Patient and public involvement (PPI) ensures clinical trials are inclusive, relevant, and aligned with societal needs. By incorporating patient perspectives, research becomes more accessible, patient-centred, and trusted. PPI builds stronger connections between researchers and communities, making trials more representative and impactful.
Effective PPI involves engaging patients in every stage of research, from design to results dissemination. Researchers work alongside participants, using clear, jargon-free communication and valuing their input. By fostering collaboration and creating accessible opportunities, trials are conducted "with" and "by" the public, ensuring outcomes benefit everyone.
Latest NEWS and MEDIA
News and media releases
COVID-19 clinical trials disproportionately run out of high-income countries, research shows
‘HOPE’ for the future - Showing the way forward for clinical trials in challenging circumstances
New Course on Randomised Clinical Trials
Clinical trials are neglecting the interplay between COVID-19 and chronic diseases, analysis shows
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