@article{16459,
  author = {Lindley Richard},
  title = {Drug trials for older people},
  abstract = {<p>
We are living in an era of unprecedented aging, with over a billion older people expected to be alive within a few decades. Despite this predictable demographic, drug trials have not kept pace with change and we now have significant evidence-practice gaps. These have arisen due to inappropriate age limits in randomized controlled trials and the near-universal exclusion of frail older people from studies. Suggested solutions include the abolition of age limits in new randomized controlled trials, and the routine measurement of frailty, with a new generation of randomized controlled trials to establish whether treatments remain effective and safe in old age and increasing frailty. We should all have a personal interest in ensuring that drugs used in our old age are truly effective.
</p>
},
  year = {2012},
  journal = {Journals of Gerontology. Series A, Biological Sciences and Medical Sciences},
  volume = {67},
  edition = {2011/05/07},
  number = {2},
  pages = {152-7},
  isbn = {1758-535X (Electronic)1079-5006 (Linking)},
  note = {Lindley, Richard IReviewUnited StatesThe journals of gerontology. Series A, Biological sciences and medical sciencesJ Gerontol A Biol Sci Med Sci. 2012 Feb;67(2):152-7. Epub 2011 May 5.},
  language = {eng},
}