00827nas a2200157   4500000000100000008004100001100002000042700001500062700001800077245008100095250001500176300001000191490000600201520041600207020004600623       2010                            d1 aLindley Richard1 aWardlaw J.1 aSandercock P.00a'Where are we now with intravenous thrombolysis for acute ischaemic stroke?'  a2010/09/22  a381-20 v53 a<p>
The publication of the updated individual patient data meta-analysis of the larger randomised trials of intravenous rt-PA for acute ischaemic stroke has re-opened the debate about how the treatment should be used in routine practice, and what information can be expected to emerge in the next 2-3 years from the ongoing trials [the largest of which is the Third International Stroke Trial (IST-3)].
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