01012nas a2200193   4500000000100000008004100001100001700042700002000059700001700079700002200096700002000118700002000138700001900158245009100177300001200268490000700280520051700287022001400804       2017                            d1 aFinfer Simon1 aBellomo Rinaldo1 aShetty Amith1 aMacdonald Stephen1 aKeijzers Gerben1 aWilliams Julian1 aShapiro Nathan00aReview article: Sepsis in the emergency department - Part 1: Definitions and outcomes.  a619-6250 v293 a<p>Sepsis has recently been redefined as acute organ dysfunction due to infection. The ED plays a critical role in identifying patients with sepsis. This is challenging due to the heterogeneity of the syndrome, and the lack of an objective standard diagnostic test. While overall mortality rates from sepsis appear to be falling, there is an increasing burden of morbidity among survivors. This largely reflects the growing proportion of older patients with comorbid illnesses among those treated for sepsis.</p>  a1742-6723