02056nas a2200229   4500000000100000008004100001100001700042700001700059700001200076700001900088700001700107700001400124700001500138700001600153700001300169700001600182245018900198300001200387490000700399520140600406022001401812       2017                            d1 aHuang Liping1 aZhang Yuhong1 aZhao Yi1 aZhang Tianjing1 aChang Xiaoyu1 aLiu Wanlu1 aLi Xiaoxia1 aWang Faxuan1 aLiao Sha1 aLiu Xiuying00aComparison of sodium, potassium, calcium, magnesium, zinc, copper and iron concentrations of elements in 24-h urine and spot urine in hypertensive patients with healthy renal function.  a104-1080 v443 a<p>Sodium, potassium, calcium, magnesium, zinc, copper and iron are associated with the sequela of hypertension. The most reliable method for testing those elements is by collecting 24-h urine samples. However, this is cumbersome and collection of spot urine is more convenient in some circumstance. The aim of this study was to compare the concentrations of different elements in 24-h urine and spot urine.</p><p><b>METHODS: </b>Data was collected from a sub-study of China Salt Substitute and Stroke Study. 240 participants were recruited randomly from 12 villages in two counties in Ningxia, China. Both spot and 24-h urine specimens were collected from each patient. Routine urine test was conducted, and concentration of elements was measured using microwave digestion and Inductively Coupled Plasma-Optical Emission Spectrometry. Partial correlation analysis and Spearman correlation analysis were used to investigate the concentration of different elements and the relationship between 24- h urine and spot urine.</p><p><b>RESULTS: </b>A partial correlation in sodium, potassium, calcium, magnesium and iron was found between paired 24-h urine and spot urine samples except copper and zinc: 0.430, 0.426, 0.550, 0.221 and 0.191 respectively.</p><p><b>CONCLUSIONS: </b>Spot urine can replace 24-h urine for estimating some of the elements in hypertensive patients with normal renal function.</p>  a1878-3252