01878nas a2200193   4500000000100000008004100001260001600042100002600058700002000084700001800104700002000122700002500142700001700167245007300184300001300257490000600270520139400276022001401670       2017                            d  c893338133851 aPecoits-Filho Roberto1 aNerbass Fabiana1 aClark William1 aSontrop Jessica1 aMcIntyre Christopher1 aMoist Louise00aOccupational Heat Stress and Kidney Health: From Farms to Factories.  a998-10080 v23 a<p>Millions of workers around the world are exposed to high temperatures, intense physical activity, and lax labor practices that do not allow for sufficient rehydration breaks. The extent and consequences of heat exposure in different occupational settings, countries, and cultural contexts is not well studied. We conducted an in-depth review to examine the known effects of occupational heat stress on the kidney. We also examined methods of heat-stress assessment, strategies for prevention and mitigation, and the economic consequences of occupational heat stress. Our descriptive review summarizes emerging evidence that extreme occupational heat stress combined with chronic dehydration may contribute to the development of CKD and ultimately kidney failure. Rising global temperatures, coupled with decreasing access to clean drinking water, may exacerbate the effects of heat exposure in both outdoor and indoor workers who are exposed to chronic heat stress and recurrent dehydration. These changes create an urgent need for health researchers and industry to identify work practices that contribute to heat-stress nephropathy, and to test targeted, robust prevention and mitigation strategies. Preventing occupational heat stress presents a great challenge for a concerted multidisciplinary effort from employers, health authorities, engineers, researchers, and governments.</p>  a2468-0249