02128nas a2200217   4500000000100000008004100001100001600042700001500058700001800073700002100091700001400112700001100126700001400137700001900151700001600170245009300186300001400279490000800293520159500301022001401896       2018                            d1 aWu Yangfeng1 aGao Runlin1 aPatel Anushka1 aBlumenthal James1 aShi Chuan1 aYu Xin1 aZhu Yidan1 aJiang Ronghuan1 aZhang Aihua00aSedentary Behavior and the Risk of Depression in Patients With Acute Coronary Syndromes.  a1456-14600 v1213 a<p>Although there is good evidence that sedentary behavior is associated with poor health outcomes in healthy persons and patients with cardiovascular disease, the mental health consequences of sedentary behavior have not been widely studied. In this report, we conducted a cross-sectional analysis to examine the relation of self-reported sedentary behavior and depression in a sample of 4,043 hospitalized men and women with acute coronary syndrome enrolled in a randomized clinical trial in rural China. Sedentary behavior was assessed by self-report, and depression was assessed with the Patient Health Questionnaire-9 (PHQ-9); a subset of 1,209 patients also completed the Beck Depression Inventory-II. Results revealed that greater sedentary behavior was associated with higher levels of depressive symptoms measured by both the PHQ-9 (p <0.001) and the Beck Depression Inventory-II (p <0.001). Compared with patients who reported that they were seldom sedentary, patients reporting that they were frequently sedentary were 4.7 times (odds ratio 4.73, 95% confidence interval 2.71 to 8.24) more likely to be clinically depressed defined as PHQ-9 scores ≥10 after adjusting for demographic factors, lifestyle behaviors, clinical characteristics, and in-hospital treatments. In conclusion, greater sedentary behavior is significantly related to greater depression in Chinese patients with acute coronary syndrome, independent of physical activity. These findings suggest that strategies to reduce sedentary behavior may improve medical outcomes and reduce risk for depression.</p>  a1879-1913