TY - JOUR
AU - Mrkobrada M.
AU - Chan M.
AU - Nagele P.
AU - Szczeklik W.
AU - Devereaux P.
AU - Alonso-Coello P.
AU - Walsh M.
AU - Berwanger O.
AU - Villar J.
AU - Wang C.
AU - Jacka M.
AU - Sigamani A.
AU - Srinathan S.
AU - Biccard B.
AU - Tiboni M.
AU - Pettit S.
AU - Botto F.
AU - Sessler D.
AU - Thomas S.
AU - Rodseth R.
AU - Pearse R.
AU - McQueen M.
AU - Kavsak P.
AU - Thorlacius L.
AU - Buse G.
AU - Hill S.
AU - Cembrowski G.
AU - de Miguel A.
AU - Graham M.
AU - Kueh J.
AU - Li S.
AU - Lit L.
AU - Martinez-Bru C.
AU - Naidoo P.
AU - Xavier D.
AU - Garcia M.
AU - Chow Clara
AB - <p>
OBJECTIVES: To determine the proportion of noncardiac surgery patients exceeding the published 99th percentile or change criteria with the high sensitivity Troponin T (hs-TnT) assay. DESIGN AND METHODS: We measured hs-TnT preoperatively and postoperatively on days 1, 2 and 3 in 325 adults. RESULTS: Postoperatively 45% (95% CI: 39-50%) of patients had hs-TnT&gt;/=14ng/L and 22% (95% CI:17-26%) had an elevation (&gt;/=14ng/L) and change (&gt;85%) in hs-TnT. CONCLUSION: Further research is needed to inform the optimal hs-TnT threshold and change in this setting.
</p>

AD - McMaster University, 1200 Main Street West, Hamilton, ON, Canada L8N 3Z5.
AN - 21640092
BT - Clinical Biochemistry
ET - 2011/06/07
LA - eng
M1 - 12
N1 - Kavsak, Peter AWalsh, MikeSrinathan, SadeeshThorlacius, LaurelBuse, Giovanna LuratiBotto, FernandoPettit, ShirleyMcQueen, Matthew JHill, Stephen AThomas, SabuMrkobrada, MarkoAlonso-Coello, PabloBerwanger, OtavioBiccard, Bruce MCembrowski, GeorgeChan, Matthew T VChow, Clara Kde Miguel, AngelesGarcia, MercedesGraham, Michelle MJacka, Michael JKueh, J HLi, Stephen C HLit, Lydia C WMartinez-Bru, CeciliaNaidoo, PrebashiniNagele, PeterPearse, Rupert MRodseth, Reitze NSessler, Daniel ISigamani, AlbenSzczeklik, WojciechTiboni, MariaVillar, Juan CarlosWang, C YXavier, DenisDevereaux, P JUnited StatesClinical biochemistryClin Biochem. 2011 Aug;44(12):1021-4. Epub 2011 May 24.
N2 - <p>
OBJECTIVES: To determine the proportion of noncardiac surgery patients exceeding the published 99th percentile or change criteria with the high sensitivity Troponin T (hs-TnT) assay. DESIGN AND METHODS: We measured hs-TnT preoperatively and postoperatively on days 1, 2 and 3 in 325 adults. RESULTS: Postoperatively 45% (95% CI: 39-50%) of patients had hs-TnT&gt;/=14ng/L and 22% (95% CI:17-26%) had an elevation (&gt;/=14ng/L) and change (&gt;85%) in hs-TnT. CONCLUSION: Further research is needed to inform the optimal hs-TnT threshold and change in this setting.
</p>

PY - 2011
SN - 1873-2933 (Electronic)0009-9120 (Linking)
SP - 1021
EP - 4
T2 - Clinical Biochemistry
TI - High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: A prospective cohort study
VL - 44
ER -