BackgroundAccording to the World Health Organization, unhealthy lifestyles relating to poor diets, physical inactivity and/or smoking are leading risk factors for cardiovascular diseases (CVD), cancer and other non-communicable diseases. The workplace is an important setting to promote health. Workplace-based disease prevention strategies have great potential to not only prevent CVD and other NCDs, but also greatly reduce the risks and burden of cancer. ObjectiveThis project will develop a scalable workplace cancer prevention and health promotion model in China; and it will implement and evaluate the effectiveness and acceptability of this model, as well as scale up in workplaces of various regions in China.InterventionThe project will conduct online and offline health promotion interventions in 15 workplaces across three Chinese cities - Xiangtan of Hunan province, Nanchang of Sichuan province, and Wuhai of Inner Mongolian autonomous region. The interventions cover the four areas: (1) health-relate

Background:About 1 in 10 adults have breathlessness, totalling over 1.8 million in Australia alone.Breathlessness (dyspnoea) is a common presenting complaint in primary care and is a symptom of cardiovascular and respiratory disease, but also associated with obesity, loss of fitness and anxiety.Breathlessness that chronically limits exertion significantly reduces quality of life and is becoming more prevalent following bushfires, consequent worsening air pollution and severe SARS-CoV-2 pandemic. Respiratory conditions account for around 10% of deaths in Australia and 31% of Australian adults have a chronic respiratory disease. There is a significant need to improve health outcomes in respiratory space, however the multifactorial nature of breathlessness challenges general practitioners’ ability to provide correct diagnosis or best management. In a recent survey of over 10,000 Australian adults, 22% reported a current respiratory or heart condition or both. Of those with a current respiratory condi

BackgroundIn India, transgender individuals face a disproportionate burden of mental illness, yet their mental health remains largely under-researched. Studies have revealed alarming statistics, such as 42.7% of transwomen experiencing moderate to severe depression and 48% suffering from psychiatric disorders. This is in stark contrast to the approximate 14% prevalence among gender conforming individuals. Recognizing mental health as a global priority, the United Nations has emphasized addressing mental illness as crucial for sustainable development.AimsOur project aims to address this pressing issue by conducting a preliminary evaluation of a peer support model tailored to the needs of transgender individuals in the National Capital Region (NCR) of Delhi. We seek to explore the effects of this model on anxiety, depression, suicide/self-harm rates, and overall psychological wellbeing. Additionally, we aim to assess the acceptability of the peer support approach and identify factors that facilitate or impede i

Hosted by The George Institute India, in partnership with Imperial College London, the NIHR Global Health Research Centre for Non-Communicable Diseases and Environmental Change aims to be a recognised centre of excellence on non-communicable diseases (NCDs) and global environmental change in low and middle-income countries (LMICs), offering world-leading research, training and policy advice for health equity. LMICs face dual, intertwined challenges of a rapidly growing burden of NCDs and the existential threat of global environmental change. In addition, health systems in LMICs face specific challenges in delivering high-quality, equitable services for NCDs prevention and care, especially for marginalised populations most impacted by environmental change.Despite an increasingly recognised imperative for action, there is a paucity of evidence on cost-effective interventions to address major challenges emerging at the nexus of NCDs and environmental change.Our Centre will focus on Bangladesh, India, and Indones

BackgroundAcute kidney injury (AKI) is caused by a loss of kidney function. This leaves the body unable to remove waste products, and balance water and electrolyte levels effectively. Some people with AKI may experience it short-term and recover their kidney function. For others, AKI may progress further and develop into chronic kidney disease (CKD), especially for those who have other co-existing conditions that require treatment. People who have recovered from AKI, however, have an increased risk of other health problems or even having AKI again in the future.A new class of oral anti-hyperglycaemic drugs, called sodium glucose co-transporter 2 (SGLT2) inhibitors, were initially used in the treatment of T2DM. They work by increasing the removal of glucose, and in turn lowering blood glucose levels.There is now a growing amount of research evidence to show SGLT2 inhibitors have additional benefits in people who are at risk of cardiovascular and kidney disease. SGLT2 inhibitors have been shown t

The Blood In Action project will work with the community and experts in infection and pregnancy to make use of thousands of blood samples provided by women during their maternity care to examine how diseases transmit from person to person. Blood samples of pregnant women receiving NHS pregnancy care are stored for two years in case of suspected exposure to infection in the mother or baby. These samples can be tested for existing antibodies (a marker of immunity) and linked to information about age, ethnicity, and deprivation, to build a picture of the impact of infections on women, children, and the general population. They are otherwise thrown away at 2 years. During the COVID-19 pandemic, the research team comprising colleagues from the George Institute for Global Health, UK, Imperial College London, and the Imperial College Healthcare NHS Trust used these samples to map the spread of the virus in North-West London, over time and in different groups of women. This 3-year project will extend this wo

Background Children with disabilities and medical conditions often are not able to travel in regular child restraint systems. Specialty harnesses and vests have been designed in response to motor vehicle transport needs for children with medical conditions, however, Australian standards do not cater for the harnesses and vests as most are manufactured overseas and there is a lack of research regarding their design, construction, and safety performance. Aims The study aims to understand access to, and the use of specialty harnesses and vests used by children with disabilities and medical conditions when travelling in motor vehicles in Australia and New Zealand. The results will assist in the development of guidance and standards for the adoption and use of harnesses and vests in Australia and New Zealand. Eligibility Criteria The research study is looking to recruit people who meet the following criteria: Are you aged 18 years or over? Are you the parent or carer of a child