DAYARA: Developing and testing An intervention to promote psYchological wellbeing Among Scheduled TRibe communities in Andhra Pradesh
Background:
More than 104 million (approximately 8%) of India’s population belongs to Scheduled Tribe (ST) communities. About 35% of STs live below the poverty line and compared to other social groups, have poorer health and social indicators. Many live in remote areas or forest areas and have poor physical access to health facilities. ST communities have also been disproportionately affected by displacement and forced migration due to development projects. Although ST communities are exposed to a combination of social, economic and environmental factors that may affect their mental health and wellbeing, there is limited data related to mental health needs of tribal communities in India, with few mental health interventions involving tribal communities and limited evidence of appropriate mental health promotion interventions. Mental health promotion (MHP) is based on broader principles of health promotion in which the focus is not on disease or pathology but on promoting overall health and ps
The George Institute for Global Health 2025-26 Pre-Budget Submission
Policy & Practice Report
Clinical and community trials
About this study
Individuals receiving dialysis are at risk of heart failure and heart-related death. There is an urgent need for treatments that reduce the risk of these problems in patients that require dialysis.
Spironolactone is a medication used to prevent heart failure and related deaths in patients that do not require dialysis. It works by blocking a hormone (aldosterone) in your body that causes high blood pressure and can damage the heart. Although spironolactone is very effective in patients that do not require dialysis, we do not know if spironolactone is effective in dialysis patients. Our research will help determine if spironolactone reduces heart failure and heart related deaths in dialysis patients.
Recruitment criteria
Inclusion
Age
≥45 years or
≥18 with a history of diabetes
On dialysis ≥ 90 days
On either
Haemodialysis prescribed at least 2 treatments per week or
Peritoneal dialysis prescribed with at least 1 exc
Clinical and community trial
About the study
Chronic Obstructive Pulmonary Disease (COPD) is the third-leading cause of global health-related disease and deaths. Heart disease is very common in people diagnosed with COPD and is often the cause of health-related sickness and hospitalisations, causing 30 – 50% of deaths. Studies repeatedly show that heart disease is often not diagnosed in persons with COPD, and when it is diagnosed it is often under-treated. People with COPD are also commonly not included in clinical trials of drugs which treat heart disease and heart-related deaths.
Beta (β)-blockers are medications often used to treat heart disease. In this study, we will be investigating whether pro-active treatment with a β-blocker in people with COPD can reduce heart-related events, such as strokes and heart attacks. This is important for people with COPD with either known or unknown underlying heart disease. The study also aims to investigate whether this treatment influences number of respiratory flare ups (exace
Clinical and community trial
About this study
Australians are increasingly shopping online for their groceries however we don’t have much evidence on the level of influence of information available to consumers online. The aim of this research is to understand how online grocery purchasing choices may change depending on the information being presented online.
Recruitment criteria
Aged 18-75
Have high blood pressure
Diagnosed by your doctor or currently taking a stable dose of blood pressure lowering medications
Regularly purchase most of their groceries online from Woolworths and plan to continue for the duration of the study (4 months) or for those who don’t currently shop with Woolworths, you will also be eligible if you switch to shopping at Woolworths for the duration of the study
Would be willing to shop for their groceries online for the study
What’s involved?
Participants will be asked to complete the following research activities if they consent to join t
SUcceSS: SUrgery for Spinal Stenosis – a randomised placebo-controlled trial
Background
Lumbar spinal stenosis (LSS) is a common and debilitating condition that primarily affects individuals over 50. It results from degenerative changes in the structures surrounding the spinal canal—such as the intervertebral discs, facet joints, and ligaments—that lead to a narrowing of the central lumbar spinal canal. People with LSS often experience pain, numbness, or weakness in one or both legs, which worsens with standing or walking but is relieved by sitting or bending forward.
When symptoms do not improve with conservative treatments like medication or physiotherapy, surgery is often recommended. Decompression surgery, such as a laminectomy or laminotomy, involves removing bone and ligament tissue that contribute to the narrowing of the spinal canal. While some individuals experience symptom relief following surgery, strong evidence supporting the efficacy of this approach is still lacking.
Aim
This project aims to evaluate the efficacy, safety and cost-effect
Participation in the Third WHO Infodemic Manager Training
Background
An infodemic according to the WHO is “an overabundance of information, both online and offline”, and typically accompanies outbreaks and pandemics e.g. COVID-19. Mis- and dis-information have wide ranging serious and adverse impacts on individuals, communities and health systems, and undermines public health responses to COVID-19.
The 3rd WHO IM training is aimed to address the critical and urgent global need to develop capacity in infodemic management interventions and practice to understand and mitigate the impact of infodemics in a timely manner.
Aim
The 3rd IM training is aimed to build capacity so that trainees will be able to apply their knowledge and skills gained in national preparedness and response to infodemics and support the development of networks for knowledge and resource exchange
The training will encompass global and region-specific topics in the infodemic and health misinformation
Research Methodology
The virtual tr
Global Surgery and Trauma Research
An estimated 11–32% of the global disease burden is due to surgically correctable illnesses. Lancet Commission on Global Surgery estimated that 5 billion people do not have adequate access to safe affordable surgical care when needed. Contrary to belief, investing in surgical services in low- and middle-income countries (LMICs) is affordable, saves lives, and promotes economic growth. Global Surgery is defined as an area of study, research, practice, and advocacy that seeks to improve health outcomes and achieve health equity for all people who need surgical and anaesthesia care, with a special emphasis on underserved populations and populations in crisis. Among these surgically treatable diseases, trauma causes over four million deaths annually, predominantly in LMICs and is an important aspect of Global surgery. Cancer, similarly, is the second most lethal noncommunicable disease after cardiovascular disease and accounted for about 9.9 million deaths, globally in 2020. Around 9% of all cancer death
Discover the science behind our social media campaign
Women are twice as likely to die as men in the month after a heart attack.Source: The European Society of Cardiology
Women are up to 70% more likely to have adverse reactions to new medicines than men.Source: American Journal of Clinical Dermatology
Only 22% of early-stage clinical trial participants are women.Source: British Journal of Clinical Pharmacology
Women are more likely to develop dementia than men.Source: The George Institute for Global Health
Stroke misdiagnosis is more common in women than in men, because of gender differences in symptoms.Source: International Journal of Stroke
Greater gender equality is linked to longer life expectancy in women and men.Source: The George Institute for Global Health
Pregnancy as an opportunity to improve lifelong health, SMARThealth Pregnancy
Background
Pregnancy complications such as high blood pressure (also known as hypertension), gestational diabetes and anaemia increase risks to the mother and baby during pregnancy the world over, but the burden is particularly great in certain contexts, including many parts of rural India.
These complications can have longer-term consequences after birth. For instance, up to 50% of women who experience gestational diabetes will go on to develop type 2 diabetes within 5-10 years. Meanwhile, following preeclampsia (a disorder of pregnancy that is marked by the onset of high blood pressure), women are at increased risk of cardiovascular complications, while anaemia (which over half of the women in India experience during their pregnancy) can markedly affect a woman’s well-being, energy and productivity in society if it persists.
These challenges are coupled with the reality that non-communicable diseases (NCDs) such as cardiovascular diseases and diabetes are two of the l
The CEDAW Index
The United Nations (UN) treaty body system is a powerful mechanism for promoting human rights. The UN influences government action through monitoring, programs, and country-specific recommendations.
In the context of women’s rights, the Committee on the Elimination of All Forms of Discrimination Against Women (CEDAW) influences government action by periodically reviewing 189 countries every four years. Governments report on their progress ahead of each review, and civil society organisations offer grassroots perspectives to the Committee in the form of ‘shadow reports’ which validate or challenge government narratives.
The problem
A significant challenge limiting the potential of the UN treaty body system is that the CEDAW Committee lacks clarity on the implementation of its recommendations, and their overall effectiveness in achieving health and social outcomes.
Despite its 40-year history, CEDAW lacks a systematic monitoring tool to track implementation. Government
Join Us: Strengthening Australia’s research capability
Background
Australia is a world leader in health and medical research, however an ongoing research barrier is the slow recruitment of research participants across the country.
Increasing community involvement in medical research is a key goal for the government’s “National One Stop Shop” for clinical trials.
Research registers are a proven way of connecting patients and researchers, but these registers typically address specific diseases, focus on people attending metropolitan centres of excellence, and can be difficult for patients to navigate.
Disease-agnostic research registers offer participants of all types a single point of access to research.
Aims
Join Us is a not-for-profit, disease-agnostic health research register dedicated to connecting everyday Australians with meaningful research opportunities.
Join Us aims to achieve better health and wellbeing for the Australian community by removing a major barrier to the recruitment of participant